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Org 6582

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Chemical compound

Pharmaceutical compound
Org 6582
Identifiers
  • (1S,9S,13R)-5-chlorotricyclo[7.3.1.02,7]trideca-2(7),3,5,10-tetraen-13-amine
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC13H14ClN
Molar mass219.71 g*mol-1
3D model (JSmol)
  • C1C=C[C@@H]2CC3=C([C@H]1[C@@H]2N)C=CC(=C3)Cl
  • InChI=1S/C13H14ClN/c14-10-4-5-11-9(7-10)6-8-2-1-3-12(11)13(8)15/h1-2,4-5,7-8,12-13H,3,6,15H2/t8-,12+,13-/m1/s1
  • Key:OQLNPMOPMXMVAH-OXHMUOHRSA-N

Org 6582 is a selective serotonin reuptake inhibitor (SSRI) which was never marketed.[1][2]

It is an analogue of para-chloroamphetamine (PCA) and 6-chloro-2-aminotetralin (6-CAT).[1]

See also

[edit]
  • Metazocine - structural analog that is a functional opioid instead of MAT inhibitor

References

[edit]
  1. ^ a b Fuller RW (June 1978). "Structure-activity relationships among the halogenated amphetamines". Annals of the New York Academy of Sciences. 305: 147-159. doi:10.1111/j.1749-6632.1978.tb31518.x. PMID 152079.
  2. ^ Mireylees SE, Goodlet I, Sugrue MF (April 1978). "Effects of ORG 6582 on monoamine uptake in vitro". Biochemical Pharmacology. 27 (7): 1023-1027. doi:10.1016/0006-2952(78)90152-1. PMID 656149.
DATTooltip Dopamine transporter
(DRIsTooltip Dopamine reuptake inhibitors)
NETTooltip Norepinephrine transporter
(NRIsTooltip Norepinephrine reuptake inhibitors)
SERTTooltip Serotonin transporter
(SRIsTooltip Serotonin reuptake inhibitors)
VMATsTooltip Vesicular monoamine transporters
Others

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