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Computational Diabetology

The CoDia Lab

Our research group develops bioinformatics methods for analyzing molecular high-throughput data in the context of diabetes research. We address computational challenges arising from large-scale and heterogeneous data, integrating multi-omics and clinical datasets to improve our understanding of metabolic dysfunctions and their relationship with cardiovascular diseases. We develop pangenome-based approaches to study disease-related genetic variations, particularly in complex loci relevant to diabetes. Our work also extends to modeling epigenetic gene regulation and investigating structural genomic variations to reconstruct mutation histories.

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  1. panacus panacus Public

    Panacus is a tool for computing statistics for GFA-formatted pangenome graphs

    Rust 119 11

  2. GFAffix GFAffix Public

    GFAffix identifies walk-preserving shared affixes in variation graphs and collapses them into a non-redundant graph structure.

    Rust 37 5

  3. spp-dcj spp-dcj Public

    Python 3

  4. sqz sqz Public

    /'skuzi/

    Rust 10 1

  5. trim-graph trim-graph Public

    Simple tool to remove segments and links from GFA files that are not covered by paths

    Rust

  6. ml_helpers ml_helpers Public

    Rust

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