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Octamoxin

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Octamoxin
Skeletal formula of octamoxin
Names
Preferred IUPAC name
1-Methylheptylhydrazine[citation needed]
Systematic IUPAC name
Octan-2-ylhydrazine[1]
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C8H20N2/c1-3-4-5-6-7-8(2)10-9/h8,10H,3-7,9H2,1-2H3 Y
    Key: FODQIVGFADUBKE-UHFFFAOYSA-N Y
  • CCCCCCC(C)NN
Properties
C8H20N2
Molar mass 144.262 g*mol-1
Density 0.831 g/mL
Boiling point 228 degC (442 degF; 501 K)
Pharmacology
Oral
Related compounds
Related compounds
Tuaminoheptane
Except where otherwise noted, data are given for materials in their standard state (at 25 degC [77 degF], 100 kPa).
Chemical compound

Octamoxin (trade names Ximaol, Nimaol), also known as 2-octylhydrazine, is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine class that was used as an antidepressant in the 1960s but is now no longer marketed.[2][3][4][5]

See also

[edit]

References

[edit]
  1. ^ "Octamoxin - Compound Summary". USA: National Center for Biotechnology Information. 26 March 2005. Identification and Related Records. Retrieved 31 May 2012.
  2. ^ Ganellin CR, Triggle DJ (21 November 1996). Dictionary of pharmacological agents - Google Books. CRC Press. ISBN 9780412466304.
  3. ^ "13-06781. Octamoxin [Archived]: The Merck Index".
  4. ^ Levy J, Michel-Ber E (1966). "[Relations between the antidepressive effects of octamoxine revealed by 3 pharmacological tests and inhibition of cerebral monoamine oxidase in mice]". Therapie (in French). 21 (4): 929-45. PMID 5925088.
  5. ^ Gayral L, Stern H, Puyuelo R (1966). "[Indications and results of the treatment of mental depression by octamoxine (ximaol)]". Therapie (in French). 21 (5): 1183-90. PMID 5976767.
SSRIsTooltip Selective serotonin reuptake inhibitors
SNRIsTooltip Serotonin-norepinephrine reuptake inhibitors
NRIsTooltip Norepinephrine reuptake inhibitors
NDRIsTooltip Norepinephrine-dopamine reuptake inhibitors
NaSSAsTooltip Noradrenergic and specific serotonergic antidepressants
SARIsTooltip Serotonin antagonist and reuptake inhibitors
SMSTooltip Serotonin modulator and stimulators
Others
TCAsTooltip Tricyclic antidepressants
TeCAsTooltip Tetracyclic antidepressants
Others
Non-selective
MAOATooltip Monoamine oxidase A-selective
MAOBTooltip Monoamine oxidase B-selective
Miscellaneous
Non-specific
AAADTooltip Aromatic L-amino acid decarboxylase
MAOTooltip Monoamine oxidase
Phenethylamines
(dopamine, epinephrine,
norepinephrine)
PAHTooltip Phenylalanine hydroxylase
THTooltip Tyrosine hydroxylase
DBHTooltip Dopamine beta-hydroxylase
PNMTTooltip Phenylethanolamine N-methyltransferase
COMTTooltip Catechol-O-methyl transferase
Tryptamines
(serotonin, melatonin)
TPHTooltip Tryptophan hydroxylase
AANATTooltip Serotonin N-acetyl transferase
ASMTTooltip Acetylserotonin O-methyltransferase
Histamine
HDCTooltip Histidine decarboxylase
HNMTTooltip Histamine N-methyltransferase
DAOTooltip Diamine oxidase


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