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Metomidate

Metomidate is a non-barbiturate imidazole that was discovered by Janssen Pharmaceutica in 1965 and under the names (Hypnodil, Nokemyl) is sold as a sedative-hypnotic drug used in Europe to treat humans and for veterinary purposes.

¹¹ C-labelled metomidate (11C-metomidate), may be used with positron emission tomography (PET). For instance, to detect tumors of adrenocortical origin.

GABA _B

H ₁ a ₂-Adrenergic

5-HT _2A Melatonin

Orexin

a ₂ d VDCC

Others

Cannabinoids (e.g., cannabis, tetrahydrocannabinol/dronabinol, nabilone, cannabidiol, Zenivol)
Chlorophenylalkyldiols
Diethylpropanediol
Evoxine
Fenadiazole
GABA reuptake inhibitors (e.g., tiagabine)
Guaifenesin-related muscle relaxants
Midaflur
Opioids (e.g., morphine)
Passion flower
Phemerazole
Scopolamine
Serotonin precursors (e.g., tryptophan, 5-hydroxytryptophan (5-HTP; oxitriptan))
Trazodone
UMB68
Valnoctamide

^# WHO-EM
⁺⁺ Withdrawn from market
Clinical trials:
- ⁺ Phase III
- ^SS Never to phase III

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This page was last edited on 31 December 2025, at 12:02 (UTC).
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